Ageing and Dementia Current and Future Concepts by Prof. K. A. Jellinger MD (auth.), Prof. Dr. Kurt A. PDF

By Prof. K. A. Jellinger MD (auth.), Prof. Dr. Kurt A. Jellinger, Prof. Dr. Reinhold Schmidt, Dr. Manfred Windisch (eds.)

ISBN-10: 3211837965

ISBN-13: 9783211837962

ISBN-10: 3211837973

ISBN-13: 9783211837979

ISBN-10: 3709161398

ISBN-13: 9783709161395

Epidemiological reports, sleek medical, neuroimaging, neuropsychological, molecular organic, and genetic reports have significantly better our wisdom approximately growing older approaches of the human mind, its sequelae, diagnostic, and healing probabilities and boundaries. as well as Alzheimer's sickness and different degenerative dementias, the impression of cerebrovascular lesions and their chance elements within the pathogenesis of cognitive issues of the elderly are more and more said, and the popularity of light cognitive impairment as a widespread preliminary degree of constructing dementia is changing into an more and more very important diagnostic and healing challenge. The incorporated papers have been provided on the seventh foreign Symposium in Graz, Sept. 2001 and provides a well timed review of the present and destiny thoughts of pathogenesis, prognosis, and remedy ideas of pathological mind growing old and dementias, early popularity of light cognitive impairment and destiny possiblities of prevention of dementing processes.

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S. s. Severe (%) RS * Study Any (%) WML Table 2. Prevalence of WML and silent lacunar infarcts in population-based studies with MR imaging e:.. e-e (l> ~ £ e III <: ~ rJ w o Frequency of white matter lesions and silent lacunar infarcts 31 with neurological or psychiatric disease and those with an abnormal neurological examination were excluded. The prevalence of any WML in the CHS and Rotterdam Scan Study is almost 100%. In contrast with the other studies no participants below the age of 60 years were included.

For MRI most widely used scales are the scales of Manolio, Fazekas, Schmidt, and Scheltens. Most recently a new scale extending earlier suggestions has been introduced by Wahlund et al. applicable for both CT and MRI. This article will review strengths and weaknesses of these rating scales and will discuss further requirements and future perspectives. Introduction The detection of cerebral white matter changes (WMC) on computed tomography (CT) or magnetic resonance imaging (MRI) led to considerable discussion concerning the clinical relevance of these abnormalities.

1992) Magnetic resonance imaging signal hyperintensities in the deep and subcortical white matter. A comparative study between stroke patients and normal volunteers. Arch Neurol49: 825-827 Schmidt R, Hayn M, Fazekas F, Kapeller P, Esterbauer H (1996) Magnetic resonance imaging white matter hyperintensities in clinically normal elderly individuals. Corre- Frequency of white matter lesions and silent lacunar infarcts 39 lations with plasma concentrations of naturally occurring antioxidants. Stroke 27: 2043-2047 Schmidt R , Fazekas F, Hayn M, Schmidt H, Kapeller P, Roob G, et al.

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Ageing and Dementia Current and Future Concepts by Prof. K. A. Jellinger MD (auth.), Prof. Dr. Kurt A. Jellinger, Prof. Dr. Reinhold Schmidt, Dr. Manfred Windisch (eds.)


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